罗春雄
Professor

Gender:Male

Alma Mater:北京大学

Education Level:With Certificate of Graduation for Doctorate Study

[MORE] Honors and Titles:

2014-07-01  宝洁奖教金

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研究兴趣:

近期的细胞动力学分析以及定量的生物学研究中,一些新的方法例如微流控技术已经开始被广泛的应用。其能精确的控制细胞 / 细菌所处的微环境,较高时空精度的记录细胞 / 细菌的表型行为,蛋白表达水平的变化,同时高通量的进行实验对照为细胞水平的动力学研究提供了最佳的实验工具。 我们的研究兴趣在于利用自主研发的高通量细胞动力学分析系统来进行例如酵母细胞应激响应,衰老机制,大肠杆菌耐药性,细胞及细菌趋化性等生物学问题的定量研究.

短期访问:

香港浸会大学 2003 年 7-9 月 DNA 的表面修饰,法国巴黎高师 / 巴黎十一大 2005 年 7-9 月 微流控技术,日本京都大学 2008 年 10 月 -2009 年 1 月 微结构在胚胎干细胞培养以及诱导分化中的应用。2011年5月-2011年7月,时空NO气体释放控制及细胞响应机制.短期访问:香港浸会大学 2003 年 7-9 月 DNA 的表面修饰,法国巴黎高师 / 巴黎十一大 2005 年 7-9 月 微流控技术,日本京都大学 2008 年 10 月 -2009 年 1 月 微结构在胚胎干细胞培养以及诱导分化中的应用。2011年5月-2011年7月,时空NO气体释放控制及细胞响应机制.

2006.7-2008.6 主持中国博士后基金编号20060400373 物理学方向

2007.1-2010.12 科研骨干参与自然科学基金重点项目"微流的物性与流动规律"

2008.1-2010.12 主持自然科学基金青年项目"微流体系中的纳升液滴间的反应控制"

2012.1-2015.12 主持自然科学基金面上项目"生命体在时空变化微环境下的响应行为的定量研究"

        2015.1-2019.12,作为科研骨干参与国家自然科学基金重点项目“细胞迁移动力学研究”课题编号: 11434001

   2017.1-2020.12,主持自然科学基金面上项目“基于高通量微流技术的酵母细胞蛋白动力学图谱及调控网络研究”课题编号:11674010

   2019.7-2024.6 科研骨干参与重大专项“ 生物元器件标准化设计组装与应用”课题编号:2018YFA0900703

   2020.1-2023.12 主持自然科学基金面上项目“ 应用微流系统研究癌细胞力化耦合迁移以及干细胞分化过程中的粘弹性质变化路径”,课题编号:11974002

2020.4-2025.3 科研骨干参与重大专项“鲁棒性人工基因元器件的设计原理与应用”;编号:2020YFA0906900

2024.1-2024.12 主持北京大学成都前沿交叉学科研究院 课题项目

2024.1-2027.12,主持自然科学基金面上项目“精准可控环境下的酵母细胞应激响应和衰老进程的定量研究”课题编号: 12374203

同时得到介观物理重点实验室经费支持。

Lab on a chip,Biomicrofluidics等杂志审稿人。

欢迎对交叉学科感兴趣的本科生,研究生加入。

发表论文:

91. Sijing Chen, Yanhong Sun, Fengyu Zhang, Chunxiong Luo*Dynamic processes of fate decision in inducible bistable systems, Biophysics Journal, 2024,123, 4030–4041.通讯作者

90.Kaiyue Chen, Nan Rong, Chanqiong Zhang, Jian Xu, Hao He, Wenying Liu, Yinjia Xu, Yanzhao Wu, Qi Ouyang, Yunlong Zhou*, Yaojun Yu*, Wei Yang*, Chunxiong Luo*;A Multi‐Volume Microfluidic Device for Automated and Wide Dynamic Range Digital LAMP Applications, Adv. Mater. Technol. 2024, 2401366, 通讯作者.

89. Kong, Ka Kit; A phase diagram structure determines the optimal sensitivity-precision trade-off in signaling systems, Communications Physics, 2024,7(1),80.

88. Kong, Ka Kit; Liu,Feng, Tuning the diffusion constant to optimize the readout of positional information of spatial concentration patterns, Chinese physics B,2024,33(8),088703.

87.Deng, YudanLi, LingjunXu, JianYao, YiliDing, JiangtaoWang, LeiLuo, ChunxiongYang, WeiLi, Lingli, A biomimetic human disease model of bacterial keratitis using a cornea-on-a-chip system, Biomaterials Science, 2024, 12(20),5239-5252.

86. Zhang, AnxinLi, SijiaZhang, ShuChen, SijingLou, ChunboCai, LeiChen, YihuaLuo, Chunxiong*; Yin, Wen-Bing*,Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products, Advanced Science, 2024,2407195,通讯作者

85. Hexuan Zhang , Lingjun Li , Xiaoqiang Sun, Benxiang Hou* Chunxiong Luo*, Research and development of microenvironment's influence on stem cells from the apical papilla – construction of novel research microdevices: tooth-on-a-chip, Biomedical microdevices, 2024,26,33,通讯作者

84. Hexuan Zhang , Lingjun Li* , Shujing Wang , Xiaoqiang Sun, Chunxiong Luo*, Benxiang Hou*,Construction of dentin-on-a-chip based on microfluidic technology and  tissue engineering ,Journal of Dentistry ,2024,146:105028,通讯作者

83. Wei Fu, Shujing Wang, Qi Ouyang* and Chunxiong Luo* ,A multilayer microf luidic system for studies of the dynamic responses of cellular proteins to oxygen switches at the single-cell level,Integrative Biology,2024, 16,011,通讯作者

82. Jie Hong, Hao He, Yinjia Xu,Shujing Wang and Chunxiong Luo*,An integrative temperature-controlled microfluidic system for budding yeast heat shock response analysis at the single-cell level,Lab on a Chip,2024,DOI: 10.1039/d4lc00313f, 通讯作者

81.Yanhong Sun; Fengyu Zhang; Qi Ouyang; Chunxiong Luo* ; The dynamic-process characterization and prediction of synthetic gene circuits by dynamic delay model, iScience, 2024, 27: 109142,通讯作者.

80. Lusi Li; Xuanqi Zhang; Yanhong Sun; Qi Ouyang; Yuhai Tu; Chunxiong Luo* ; Phenotypic Variability Shapes Bacterial Responses to Opposing Gradients, PRX Life, 2024, 2(2): 013001,通讯作者. 

79. Nan Rong, Kaiyue Chen, Jiqi Shao, Qi Ouyang, and Chunxiong Luo*,A 3D Scalable Chamber-Array Chip for Digital LAMP,ANALYTICAL CHEMISTRY,2023, 95, 20, 7830–7838,通讯作者. 正封面文章

78. Wei Yang#, Lei Hou#* and Chunxiong Luo*,When Super-Resolution Microscopy Meets Microfluidics:  Enhanced Biological Imaging and Analysis with  Unprecedented Resolution,Small,2023, 2207341,通讯作者.

77. Jialin Shi, Jian Xu, Yaojun Yu, Chengyuan Wu, Jiangnan Chen, Shuangshuang Li, Qi Ouyang, Wei Yang*, Chunxiong Luo*, A Parallelable 3D Microfluidic Chip for Circulating-Tumor-Cell Capture at Ultra-High Throughput and Wide Flow Rate Range,Advanced NanoBiomed Research,2023, 2200140,通讯作者.

76. Wenting Shen, Ziqing Gao, Kaiyue Chen, Alusi Zhao, Qi Ouyang, and Chunxiong Luo*, The regulatory mechanism of the yeast osmoresponse under different glucose concentrations, 2023,iScience, 26, 105809, 通讯作者.

75. Yanhong Sun, Fengyu Zhang, Lusi Li, Kaiyue Chen, Shujing Wang, Qi Ouyang, and Chunxiong Luo*,Two-Layered Microfluidic Devices for High-Throughput Dynamic Analysis of Synthetic Gene Circuits in E. coli,ACS Synthetic Biology,2022,11 (12), 3954-3965,通讯作者,正封面文章

74.Hongcun Zhu,   Wenting Shen,  Chunxiong Luo* ,  Feng Liu* ,An integrated microfluidic device for multiplexed imaging of spatial gene expression patterns of Drosophila embryos, Lab on a chip, 2022, 22, 4081-4092, 通讯作者,正封面文章

73. Zhiwei Ye#, Wei Yang#*, Ying Zheng, Shujing Wang, Xiaodong Zhang, Haibo Yu, Shuangshuang Li, Chunxiong Luo*, Xiaojun Peng*, Yi Xiao*, Integrating a Far-Red Fluorescent Probe with a Microfluidic Platform for Super-Resolution Imaging of Live Erythrocyte Membrane Dynamics, Angewandte Chemie International Edition, 2022, e202211540 ,通讯作者.

72. Xiao Li, Jialin Shi, ZiqingGao, Jian Xu, ShujingWang, Xin Li, Qi Ouyang,  Chunxiong Luo*, Biophysical studies of cancer cells’ traverse-vessel behaviors under different pressures revealed cells’ motion state transition, Scientific Reports , 2022, 12:7392, 通讯作者.

71. Xiao Li,Yiteng Jin,Jialin Shi,Xiaoqiang Sun,Qi Ouyang,Chunxiong Luo*,A high throughput microfluidic system with large ranges of applied pressures for measuring the mechanical properties of single fixed cells and differentiated cells,  Biomicrofluidics, 2022, 16, 034102 , 通讯作者. 

70. Jing Zhang, Wenting Shen, Zhiyuan Cai, Kaiyue Chen, Qi Ouyang, Ping Wei, Wei Yang*, Chunxiong Luo*, Microfluidic-Enabled Multi-Cell-Densities-Patterning and Culture Device for Characterization of Yeast Strains’ Growth Rates under Mating Pheromone, Chemosensor,  2022, 10(4), 141, 通讯作者.

69. Fengyu Zhang, Yanhong Sun, Yihao Zhang, Wenting Shen, Shujing Wang, Qi Ouyang, Chunxiong Luo*, Independent control of amplitude and period in a synthetic oscillator circuit with modified repressilator, Communications Biology, 2022, 5, 23, 通讯作者.

68.  Kaiyue Chen#, Wenting Shen#, Ziqing Gao, Chunxiong Luo*, Stress response capacity analysis during aging and possible new insights into aging studies, Current Genetics, 2021, 67(3):1-4.通讯作者.

67. Fengyu Zhang#, Yanhong Sun#, Chunxiong Luo*,  Microfluidic approaches for synthetic gene circuits' construction and analysis, Quantitative Biology,2021, 9 (1): 47-60.通讯作者.

66. Chunyang Lu#, Jian Xu#, Jintao Han, Xiao Li, Ningtao Xue, Jinsong Li, Wenhua Wu, Xinlei Sun, Yugang Wang, Qi Ouyang, Gen Yang*, Chunxiong Luo* ,  A novel microfluidic device integrating focus-separation speed reduction design and trap arrays for high-throughput capture of circulating tumor cells, Lab on a Chip, 2020, 20,4094-4105 , 通讯作者.

65. Ziqing Gao, Jian Xu, Kaiyue Chen, Shujing Wang, Qi Ouyang and Chunxiong Luo*,Comparative analysis of yeast replicative lifespan in different trapping structures using an integrated microfluidic system, Advanced Materials Technologies, 2020, 5(12):2000655, 通讯作者.

64. Kaiyue Chen, Nan Rong, Fangzheng Xiong, Qi Ouyang, Chunxiong Luo*, A novel two-layer-integrated microfluidic device for high-throughput yeast proteomic dynamics study at single cell level, Integrative Biology,2020,12(10) 241-249,通讯作者

63. Kaiyue Chen, Wenting Shen, Zhiwen Zhang, Fangzheng Xiong, Qi Ouyang, Chunxiong      Luo*, Age-dependent decline in stress      response capacity revealed by protein dynamics analysis, Scientific reports,2020, 10:15211,通讯作者

62. Hongcun Zhu, Yeping Cui, Chunxiong Luo, Feng Liu*, Quantifying Temperature compensation of Bicoid gradients with a fast T-tunable microfluidic device, Biophysical Journal, 2020, 119,1-11.

61. Jian Xu, Xudong Wang, Xiao Li, Gen Yang, Chunxiong Luo*,     High-throughput cell migration assay under combinatorial chemical environments by a novel 24-well-plate based device.Biomedical Microdevices, 2020, 22, 40, 通讯作者

60.  Lingjun Li, Tian Wu, Ying Wang, Min Ran, Yu Kang, Qi Ouyang, Chunxiong Luo*, Spatial coordination in mutually beneficial bacterial community enhances its antibiotic resistance. Communications Biology,2019, 2: 301, 通讯作者

59.  Xing Shi#, Changjun Shao#, Chunxiong Luo#, Yanan Chu, Jian Wang, Qingren Meng, Jun Yu, Zhancheng Gao, Yu Kang,Microfluidics-Based Enrichment and Whole-Genome Amplification Enable Strain-Level Resolution for Airway Metagenomics.mSystem, 2019, 4(4)e00198-19,共同一作

58.  Xiang Zhao, Chunxiong Luo*, Hongli Wang*, Protein dynamic analysis of the budding yeast sporulation process at the single-cell level in an air-enriched microfluidic device. Integrative Biology , 2019, 11(3) 79-86.通讯作者

57.  Xuanqi Zhang, Guangwei Si, Yiming Dong, Kaiyue Chen, Qi Ouyang, Chunxiong Luo*, and Yuhai Tu*, Escape band in Escherichia coli chemotaxis in opposing attractant and nutrient gradients, PNAS, 2019, 116(6) 2253-2258. 通讯作者

56.  Tingting Li, Yiming Dong, Zhang, Xuanqi Zhang, Ji, Xiangyu Ji, Chunxiong Luo, Chunbo Lou, Haoqian Zhang, Qi Ouyang,Engineering of a genetic circuit with regulatable multistability, Integrative Biology, 2018, 10, 474-482.

55.  Leqian Yu, Junjun Li, Jiayin Hong...Chunxiong Luo, ...Li Liu, Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells, Stem cell reports,2018, 11, 142–156.

54.  Xiaoqiang SunShaorong Li, Shujing Wan Chunxiong Luo*, Benxiang Hou*, The evaluation of E-faecalis colonies dissolution ability of sodium hypochlorite in microenvironment by a novel device. Biomedical Microdevices,2018,20, 36. 通讯作者

53.  Tian Wu, Changjun Shao, Lingjun Li,Shujing Wang, Qi Ouyang,Yu Kang*, Chunxiong Luo*,Streamline-based purification of bacterial samples from liquefied sputum utilizing microfluidics, Lab on a chip,2017,17, 3601-3608. 联系作者,背封面文章

52.  Bin Shao, Haiyu Yuan, Rongfei Zhang,Xuan Wang, Shuwen Zhang, Qi Ouyang, Nan Hao*, Chunxiong Luo*,Reconstructing the regulatory circuit of cell fate determination in yeast mating response. Plos Computational Biology, 2017,13:e1005671.联系作者

51.  Zhaojun Li, Qiuxian Cai, Xuanqi Zhang, Guangwei Si, Qi Ouyang, Chunxiong Luo*, and Yuhai Tu*,Barrier Crossing in Escherichia coli Chemotaxis, Physical Review Letters ,2017,118, 098101.联系作者

50. Kai Wei, Minghao Qiu, Rongfei Zhang, Liantong Zhou, Ting Zhang, Maosheng Yao*, Chunxiong Luo*,Single Living yEast PM Toxicity Sensor (SLEPTor) System, Journal of Aerosol Science, 2017, 107, 65-73. 联系作者

49.  Rongfei Zhang, Haiyu Yuan, Shujing Wang, Qi Ouyang, Yong Chen, Nan Hao, Chunxiong Luo*, High-throughput single-cell analysis for the proteomic dynamics study of the yeast osmotic stress response, Scientific reports,2017,7(1):42200, 联系作者

48. Qianghua Quan, Shuwen Zhang, Xudong Wang, Qi Ouyang, Yugang Wang, Gen Yang * , Chunxiong Luo * , A parallel and quantitative cell migration assay using a novel multi-well-based device.Biomedical microdevices, 2016, 18, 99. 联系作者

47. Xiaoqiang Sun, Shujing Wang, Yue Kang, Chunxiong Luo*, Benxiang Hou*, Study of invasion and colonization of E. Faecalis in microtubes by a novel device, Biomedical Microdeivces, 2016, 18,82-89,联系作者

46.  Haiyu Yuan, Rongfei Zhang, Bin Shao, Xuan Wang, Qi Ouyang, Nan Hao and Chunxiong Luo*; Protein expression patterns of the yeast mating response, Integrative Biology, 2016; 712-719, 联系作者,正封面文章

45.  Qiuxian Cai, Zhaojun Li, Qi Ouyang, Chunxiong Luo* and Vernita D.Gordon*;Singly Flagellated Pseudomonas aeruginosa Chemotaxes Efficiently by Unbiased Motor Regulation, mBio, 2016,doi: 10.1128/mBio.00013-16.联系作者

44.  Xuanqi Zhang, Lingjun Li, Chunxiong Luo*; Gel integration for microfluidic applications, Lab Chip, 2016,16, 1757-1776. 联系作者 ,综述文章

43.  Wei Yang, Chunxiong Luo*, Luhua Lai, and Qi Ouyang*, A novel microfluidic platform for studying mammalian cell chemotaxis in different oxygen environments under zero-flow conditions, Biomicrofluidics,2015, 9, 044121,联系作者

42.  Min Ran,Ying Wang, Sida Wang, Chunxiong Luo*,Pump-free gradient-based micro-device enables quantitative and high-throughput bacterial growth inhibition analysis,Biomedical Microdevices,2015, 17: 67, 联系作者

41.  Ying Wang, Min Ran, Jun Wang, Qi Ouyang*, Chunxiong Luo*, Studies of Antibiotic Resistance of Beta-Lactamase Bacteria under Different Nutrition Limitations at the Single-Cell Level, PLoS ONE ,2015, 10(5): e0127115, 联系作者

40.  Xuejun Zhu, Xin Ge, Ning Li, Long-Fei Wu, Chunxiong Luo, Qi Ouyang, Yuhai Tu and Guanjun Chen, Angle sensing in magnetotaxis of Magnetospirillum magneticum AMB-1,Integrative Biology , 2014, 6 , 706-713.

39.  Xianjie Kang, Lingli Jiang, Xi Chen, Haiyu Yuan, Chunxiong Luo*, Qi Ouyang*, Pump-free multi-well-based microfluidic system for high-throughput analysis of size-control relative genes in budding yeast, Integrative Biology , 2014, 6 , 685-693. 联系作者

38.  Weikang Wang, Yi Quan , Qibin Fu, Yu Liu, Ying Liang, Jingwen Wu, Gen Yang, Chunxiong Luo , Qi Ouyang , Yugang Wang, PLOS ONE, 2014, 9(1), e84654, 10.1371/journal.pone.0084654.

37.  Xiaorong Wang # , Yu Kang # , Chunxiong Luo # , Tong Zhao, Lin Liu, Xiangdan Jiang, Rongrong Fu, Shuchang An, Jichao Chen, Ning Jiang, Lufeng Ren, Qi Wang, Kenneth Baillie, Zhancheng Gao * , and Jun Yu * , Heteroresistance at Single Cell Level: Adapting Antibiotic Stress by Population-based Strategy and Growth-controlled Inter-phenotypic Coordination, mBio, 2014, 5(1) : e00942-13. 并列第一作者.

36.  Xiangdan Jiang, Yu Kang, Xingjie Pan, Jun Yu, Qi Ouyang,   Chunxiong Luo* , Studies of drug resistance response of sensitive and drug-resistance strains in microfluidic system,   Integrative Biology , 2014, 6:143-151( Inside front cover story) . 联系作者.

35.  ShuangYu Bi, Daqi Yu, Guangwei Si, Chunxiong Luo,Tongqing Li, Qi Ouyang, Jakovljevic, Vladimir, Sourjik, Victor, Yuhai Tu, Luhua Lai, Discovery of novel chemoeffectors and rational design of Escherichia coli chemoreceptor specificity, PNAS,2013,110:16814-16819.

34.  Yuan Tian, Chunxiong Luo* , Qi Ouyang * , A microfluidic synchronizer for fission yeast, Lab on a Chip, 2013, 13 (20), 4071 - 4077. 联系作者.

33.  Wei Yang, Zhaojun Li,Weilin Zhang, Chunxiong Luo*,Qi Ouyang, Gen Yang,Yugang Wang,A novel density control device for the study of cancer cell autocrine effect,Biomedical Microdevices,2013, 15:683-689, 联系作者

32.  Sisi Li, Jian Shi, Li Liu, Junjun Li, LM Jiang, Chunxiong Luo , Kamei K, Yong Chen , MICROELECTRONIC ENGINEERING , 2013 ,110, 70-74 .

31.  Xianjie Kang, Chunxiong Luo * , Qiong Wei, Chunyang Xiong , Qian Chen, Ying Chen, Qi Ouyang*, Mass production of highly monodisperse polymeric nanoparticles by parallel flow focusing system, Microfluidics and Nanofluidics ,2013, 15:337-345, 联系作者

30.  Xuejun Zhu, Guangwei Si, Nianpei Deng, Qi Ouyang, Tailin Wu, Zhuoran He, Lili Jiang, Chunxiong Luo *, and Yuhai Tu* ,Frequency-dependent Escherichia coli chemotaxis behaviors, Physical Review Letters ,2012,108,128101, 联系作者

29.  Guangwei Si , Wei Yang , Shuangyu Bi , Chunxiong Luo* and Qi Ouyang, A parallel diffusion-based microfluidic device for bacterial chemotaxis analysis, Lab on a Chip , 2012, 12 , 1193-1197, 联系作者.

28.  Yuan Tian , Chunxiong Luo* , Yuheng Lu , Chao Tang and Qi Ouyang*, Cell cycle synchronization by nutrient modulation ,Integrative Biology 2012 , 4 , 328-334, 联系作者

27.  Zhengwei Xie, Yi Zhang, Ke Zou, Onn Brandman, Chunxiong Luo, Qi Ouyang and Hao Li, Molecular phenotyping of aging in single yeast cells using a novel microfluidic device, Aging cell, 2012, 11, 599–606.

26.  Yi Zhang,Chunxiong Luo, Ke Zou, Zhengwei Xie, Onn Brandman, Qi Ouyang, Hao Li, Single Cell Analysis of Yeast Replicative Aging Using a New Generation of Microfluidic Device, PLOS ONE, 2012,7(11), e48275, DOI:10.1371/journal.pone.0048275.

25.  Gen Yang, Yi Quan, Weikang Wang, Qibin Fu, Jingwen Wu, Tao Mei, Jia Li, Yubo Tang, Chunxiong Luo, Qi Ouyang, Shaopeng Chen, Lijun Wu, Tom K. Hei, and Yugang Wang, Dynamic equilibrium between cancer stem cells and non-stem cancer cells in human SW620 and MCF-7 cancer cell populations. British Journal of Cancer; 106: 1512-9; 2012.

24.  Guowei Lu, Lei Hou , Tianyue Zhang, Jie Liu, Hongming Shen , Chunxiong Luo , Qihuang Gong, JOURNAL OF PHYSICAL CHEMISTRY C, 2012 ,110, 25509-25516

23.  Guowei Lu, Jie Liu, TianYue Zhang, Wenqiang Li, Lei Hou , Chunxiong Luo , Franck Lei, Michel Manfait , Qihuang Gong,NANOSCALE , 2012 , 4, 3359-3364

22.  Wang, QY; Lu, GW; Hou , L ; Zhang,; Luo , CX ; et.al, CHEMICAL PHYSICS LETTERS , 2011, 503,256-261.

21.  Chunxiong Luo, et.al,Differentiating stem cells on patterned substrates for neural network formation, 2011,Microelectronic Engineering 8, 1707-1710 第一作者

20.  Ning Li, Chunxiong Luo, et.al.Microfluidic generation and dynamically switching of oxygen gradients applied to the observation of cell aerotactic behavior, 2011, Microelectronic Engineering 8,1698-1701

19.  Chunxiong Luo # , Xiaofang Ni # , Li Liu, Shin-ichiro M. Nomura, Yong Chen*, Degassing-assisted patterning of cell culture surfaces, Biotechnology and Bioengineering , 105,2010, 854-859. 并列第一作者

18.  Li Liu # , Chunxiong Luo # , Xiaofang Ni, et.al., A micro-channel-well system for culture and differentiation of embryonic stem cells on different types of substrate, BIOMEDICAL MICRODEVICES 12,2010, 505-511, 并列第一作者

17.  Guangwei Si, Xuejun Zhu, Yangsen Kang, Chunxiong Luo *, Qi Ouyang*, Yong Chen,Diffusion-based concentration control in microcavities during long time period by programmed syringe pumps, Microelectronics Engineering 87 , 793-797 2010 联系作者

16.  Tao Zhu#, Chunxiong Luo#, Jianyong Huang, Chunyang Xiong, Qi Ouyang and Jing Fang,Electroporation based on hydrodynamic focusing of microfluidics with low dc voltage, Biomedical Microdevices, 12,2010, 35-40. 并列第一作者

15.  Xianjie Luo, YangShen Kang, Chunxiong Luo*, et al.,An automatic microturbidostat for bacterial culture at constant density,BIOMEDICAL MICRODEVICES 12: 499-503, 2010, 联系作者

14.  Li, H; Lei, L; Zeng , Q; Shi, Jian ; Luo , CX ; Ji , H; Ouyang , Q ; Chen, Y, SENSORS AND ACTUATORS B-CHEMICAL , 2010, 145,570-574.

13.  Hao Li, Chunxiong Luo, Hang Ji, Qi Ouyang and Yong Chen,Micro-pressure sensor made of conductive PDMS for microfluidic applications, Microelectronic Engineering , 87(2010), 1266-1269.

12.  Wang, L ; Ni, XF ; Luo , CX ; Zhang, ZL ; Pang, DW ; Chen, Y, BIOMEDICAL MICRODEVICES , 2009 ,11, 679-684.

11.  Chunxiong Luo , Lingli Jiang, Shibo Liang, Qi Ouyang*, Hang Ji and Yong Chen,High-throughput microfluidic system for monitoring diffusion-based monolayer yeast cell culture over long time periods , Biomedical Microdevices , 11, 2009, 981-986. 第一作者

10.  Chunxiong Luo , Xuejun Zhu, Tao Yu, XianjiaLuo, Qi Ouyang, Hang Ji, Yong Chen.A fast cell loading and high-throughput microfluidic system for long-term cell culture in zero-flow environments. Biotechnology and Bioengineering , 2008 , 101,190-195. 第一作者

9.  Chunxiong Luo , Hao Li, Chunyang Xiong, Xiaoling Peng, Qingli Kou , Yong Chen, Hang Ji , and Qi Ouyang,The combination of optical tweezers and microwell array for cell manipulation and cultivation in microfluidic device. Biomedical Microdevices , 2007, 9, 573-578. 第一作者

8.  Wang, Z. M.; Bao, K.; Xu, L. P.; Luo, C. X.; Zhang, B.; Ji, H.; Quyang, Q.; Chen, Y., Microfluidic cooling of semiconductor light emission diodes, MICROELECTRONIC ENGINEERING,2007, 1223-1226.

7.  Wang, Z. M.; Luo, X. J.; Wang, S.; Luo, C. X.;Sun, M. H.; Bao, K.; Zhang, B.; Zhang, G. Y.; Wang, Y. G.; Chen, Y. ; Ji, H.; Ouyang, Q., Light output enhancement of a GaN-based light emitting diode by polymer film imprinting, SEMICONDUCTOR SCIENCE AND TECHNOLOGY, 2007,22, 279-282.

6.  Chunxiong Luo , Xiaojing Yang, Qiang Fu, Manhui Sun, Qi Ouyang, Yong Chen, Hang Ji,Picoliter-volume aqueous droplets in oil: electrochemical detection and Yeast cell electroporation, Electrophoresis , 27 (2006) 1977-1983. 第一作者

5.  Chunxiong Luo, Qiang Fu, Hao Li, Luping Xu, Manhui Sun, Qi Ouyang, Yong Chen and Hang Ji,PDMS microfludic device for optical detection of protein immunoassay using gold nanoparticles, Lab on a Chip , 5, (2005)726-729. 第一作者.

4.  Chunxiong Luo, Manhui Sun, Luping Xu,Zhiling ZHANG, C. Crozatier, Yong CHEN ,and Hang Ji, Controllable PH gradient forming in microfluidic chips,Chin. Sci. Bull., 50 (2005) 629-631

3.  Manhui Sun, Chunxiong Luo, Xu LP, Ji H, Qi OY, Yu DP & Chen Y. Artificial lotus leaf by nanocasting. LANGMUIR 2005, 21 (19): 8978-8981

2.  Youdong Mao, Chunxiong Luo & Qi Ouyang. Studies of temperature-dependent electronic transduction on DNA hairpin loop sensor.Nucleic Acids Res 2003, 31, e108.

1.  Youdong Ma, Chunxiong Luo , Wei Deng, Guanyin Jin, Xiaomei Yu, Zhaohui Zhang, Qi Ouyang, Runsheng Chen & Dapeng Yu. Reversibly Swithable DNA Nanocompartment on Surface. Nucleic Acids Res. 2004, 32, e144.

国家专利:

一种细胞趋化分析芯片及装置,授权公告号:CN203320000U,授权公告日:2013.12.04, 专利发明人 :罗春雄,杨薇,冉敏,欧阳颀 
一种多孔单细胞观测板及其应用 , 授权公告号:CN102796659B, 授权日:2014.06.11,专利发明人 : 罗春雄 , 蒋灵俐 , 杨薇 , 姜香丹 
一种可布置不同细胞密度的微流控芯片及其应用,授权公告号:CN102796667B,授权日:2014.07.30, 专利发明人:罗春雄,杨薇,李昭君,康显阶

一种用于高通量细胞迁移研究的方法和细胞迁移研究系统(授权号 ZL 201610617882.5 ),专利发明人:罗春雄,张荣飞,张书文,杨根,王宇钢,欧阳颀 授权日2018.07.

 痰液样品中病原菌的快速提纯装置及快速提纯方法,授权公告号:ZL201710288471.0,专利发明人:康禹; 罗春雄; 邵长君; 吴天; 于军; 林强; 王建; 楚亚男; 付荣荣;  2019-6-28,

一种适用于循环肿瘤细胞捕获的微流控芯片(申请号 201910666239.5),专利发明人:杨根,罗春雄,芦春洋,许健,王宇钢,欧阳颀

一种高通量细胞培养芯片,专利申请号:202010743840.2 专利发明人罗春雄,陈凯悦,荣楠

一种多层三维数字核酸扩增芯片及其制作与使用方法,专利申请号:CN202110327830.5 专利发明人罗春雄,荣楠

一种超高流速稳定捕获循环肿瘤细胞(CTC) 的准三维芯片,实用新型;发明专利专利申请号:2021211174360;2021211200810; 2021105670917 专利发明人: 罗春雄,师加林

一种可编程温控微流系统及温度控制方法,申请号:202410651774.4,罗春雄,洪洁,徐胤嘉,王淑静

一种并行细胞培养微流控芯片,申请号:202420487410.2,罗春雄,包逸博,符为,王淑静

Research Group

[1]Name of Research Group:实验室现有成员

  • 王淑静
  • 师加林
  • 荣楠
  • 金亦腾
  • 陈思静
  • 洪洁
  • 包逸博
  • 徐胤嘉

[2]Name of Research Group:实验室过往成员

  • 孙燕红
  • 张京
  • 高子晴
  • 沈雯婷
  • 李晓
  • 张凤宇
  • 陈凯悦
  • 许健
  • 张玄麒,赵翔...
  • 2019实验室合...
  • 李玲君
  • 吴天
  • 2017合影
  • 张荣飞
  • 袁海宇
  • 李昭君
  • 蔡秋娴
  • 康显阶
  • 杨薇
  • 王颖
  • 冉敏
  • 2013年合影
  • 姜香丹
  • 司光伟
  • 田原
  • 朱学珺
  • 2006年实验室...

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