Shuwen Zhang, Shitao Zou, Deyao Yin, Lihong Zhao, Daniel Finley, Zhaolong Wu and Youdong Mao.USP14-regulated allostery of the human proteasome by time-resolved cryo-EM.Nature,605,567-574,2022,10.1038/s41586-022-04671-8 Shijian Zhang, Kunyu Wang, Wei Li Wang, Hanh T Nguyen, Shuobing Chen, Maolin Lu, Eden P Go, Haitao Ding, Robert T Steinbock, Heather Desaire, Joseph Sodroski and Youdong Mao.Asymmetric Structures and Conformational Plasticity of the Uncleaved Full-Length Human Immunodeficiency Virus Envelope Glycoprotein Trimer.J. Virol.,95,e0052921,2021,10.1128/JVI.00529-21 Humayun Sharif, Li Wang, Wei Li Wang, Venkat Giri Magupalli, Liudmila Andreeva, Qi Qiao, Arthur V. Hauenstein, Zhaolong Wu, Gabriel Núñez, Youdong Mao and Hao Wu.Structural mechanism for NEK7-mediated NLRP3 inflammasome activation.Nature,570,338-343,2019 Robustness of signal detection in cryo-electron microscopy via a bi-objective-function approach.BMC Bioinformatics,20,169,2019 Yuanchen Dong, Shuwen Zhang, Zhaolong Wu, Xuemei Li, Wei Li Wang, Yanan Zhu, Svetla Stoilova-McPhie, Ying Lu, Daniel Finley and Youdong Mao.Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.Nature,565,49-55,2018,10.1038/s41586-018-0736-4 Yanan Zhu, Wei Li Wang, Daqi Yu, Qi Ouyang, Ying Lu and Youdong Mao.Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome.Nat. Commun.,9,1360,2018,10.1038/s41467-018-03785-w Yuanchen Dong, Shuobing Chen, Shijian Zhang, Joseph Sodroski, Zhongqiang Yang, Dongsheng Liu and Youdong Mao.Folding DNA into a lipid-conjugated nanobarrel for controlled reconstitution of membrane proteins.Angew. Chem. Int. Ed.,57,2072-2076,2018,10.1002/anie.201710147 Jiayi Wu, Yong-Bei Ma, Charles Congdon, Bevin Brett, Shuobing Chen, Yaofang Xu, Qi Ouyang and Youdong Mao.Massively parallel unsupervised single-particle cryo-EM data clustering via statistical manifold learning.PLos One,12,e0182130,2017 Yanan Zhu, Qi Ouyang and Youdong Mao.A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy.BMC Bioinformatics,18,348,2017,10.1186/s12859-017-1757-y Ying Lu, Jiayi Wu, Yuanchen Dong, Shuobing Chen, Shuangwu Sun, Yong-Bei Ma, Qi Ouyang, Daniel Finley, Marc W Kirschner and Youdong Mao.Conformational landscape of the p28-bound human proteasome regulatory particle.Molecular Cell,67,322-333,2017