Chen Zhou has long been engaged in the frontier research of Experimental High Energy Physics at the Large Hadron Collider (2011-2021: ATLAS experiment, 2021-: CMS experiment) and has obtained major achievements in research on Higgs physics, searches for new physics phenomena, detector upgrades, and applications of machine learning and quantum computing to High Energy Physics research. He has published more than 30 papers in academic journals including Physical Review Letters (PRL). He has served as a convener of the Higgs-Photon (HGamma) working group of the ATLAS Collaboration, as a convener of the LHC Higgs combination analysis working group, and in other academic leadership roles. As principal investigator (PI), he has undertaken a research task of the National Key Research and Development Program of China, a research project of the National Natural Science Foundation of China, and other research projects. In 2024, he won the first prize of the Scientific Research Achievement Award of the State Key Laboratory of Nuclear Physics and Technology.