近期论文
Ø Quantitative biology of yeast cell cycle
• Critical slowing down and attractive manifold: a mechanism for dynamic robustness in yeast cell-cycle process. Physical Review E (2020)
• Stochasticity triggers activation of the S-phase checkpoint pathway in budding yeast. Physical Review X (2021)
• The multiple activations in budding yeast S-phase checkpoint are Poisson processes, PNAS Nexus(2023)2: gad342, https://doi.org/10.1093/pnasnexus/pgad342.
Ø Nonequilibrium states of living cell
• Phosphorylation energy and nonlinear kinetics as key determinants for G2/M transition in fission yeast cell cycle. arXiv:1610.09637. (Submitted to PNAS) .
• Positive and reverse mitotic wave under different phosphorylation energy (Under prepare)
• ATP hydrolysis kinetics and thermodynamics as determinants of calcium oscillation in pancreatic β cells.Phys. Rev. Research (2022) 4, 043142. https://doi.org/10.1103/PhysRevResearch.4.043142
Ø Modeling immune system
• A multicompartment mathematical model based on host immunity for dissecting COVID-19 heterogeneity. Heliyon (2022) 8(5) e09488.
• Dynamically modeling the effective range of IL-2 dosage in the treatment of systemic lupus erythematosus. iScience. (2022) 25(9):104911.
• Dynamical modelling of viral infection and cooperative immune protection in COVID-19 patients. PLoS Comput. Biol. (2023) 19(9): e1011383. https://doi.org/10.1371/journal.pcbi.1011383.